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A wide variety of techniques, methods, and tools were implemented to detect and assess mental fatigue, such as self-reporting questionnaires, attention network tests, heart rate variability, salivary cortisol levels, electroencephalogram, brain imaging, and saccadic eye movements [2,95,113,114,115,118]

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Pre-dosing with a small protein-rich snack (15-20g protein, minimal fat) 30 minutes before injection can blunt this response without negating the meal-timing strategy